Biotin, a vitamin that helps cells to produce energy, boosts nerve function in high doses, opening the door to a possible treatment for progressive forms of multiple sclerosis. Promising results of a pivotal study using high doses of the vitamin biotin in people with progressive forms of multiple sclerosis (MS) were recently presented at the [...]
Women who have acute migraine attacks that are severe enough to prompt them to seek care may be more likely to have complications when giving birth, including preterm delivery, preeclampsia and low birthweight. Women 35 and older were seven times more likely to have these complications. These findings, conducted by researchers at Montefiore Health System, [...]
A new study published in Physiological Genomics suggests that the brain shows signs of aging earlier than old age. The study found that the microglia cells—the immune cells of the brain—in middle-aged mice already showed altered activity seen in microglia from older mice. Parkinson’s, Alzheimer’s and other aging-related neurodegenerative disorders are associated with excessive inflammation [...]
Geneva: Scientists have developed a tiny implantable capsule that can turn patient's immune system against Alzheimer's disease by delivering a steady and safe flow of antibodies to the brain. One of the hypothesised causes of Alzheimer's is the over-accumulation of the protein amyloid beta (Abeta) in different areas of the brain. This results in the [...]
Cedars-Sinai research scientists have found that immune cells in the brain play a direct role in the development ofamyotrophic lateral sclerosis, or ALS, offering hope for new therapies to target the neurodegenerative disease that gradually leads to paralysis and death. The findings will appear in the journal Science on March 18, 2016. The researchers focused [...]
The objective of genetic medicine is to analyze all the genes that make up the human genome, in order to identify as many genetic diseases as possible. Indeed, each gene variation has the potential to trigger specific defects. Among all genetic conditions, diseases known as "recessive" occur only when both the father and the mother [...]
A new study published in Physiological Genomics suggests that the brain shows signs of aging earlier than old age. The study found that the microglia cells - the immune cells of the brain - in middle-aged mice already showed altered activity seen in microglia from older mice. Parkinson's, Alzheimer's and other aging-related neurodegenerative disorders are [...]
Frédéric Sedel , Brigitte Chabrol, Bertrand Audoin, Elsa Kaphan, Christine Tranchant, Tomasz Burzykowski, Ayman Tourbah, Marie T. Vanier, Damien Galanaud Abstract Niemann–Pick disease type C (NP-C) is a fatal progressive neurolipidosis involving neuronal storage of cholesterol and gangliosides. Miglustat, an inhibitor of glycosphingolipid synthesis, has been approved to treat neurological manifestations in adults and children [...]
esignation Can Expedite Review Once Submitted For FDA Approval Genentech, a member of the Roche Group, has announced that the experimental therapy ocrelizumab has been granted “Breakthrough Therapy designation” by the U.S. Food and Drug Administration (FDA) for the treatment of people with primary-progressive MS. This designation means that once Genentech files for approval of [...]
The results of a recent study suggest that brain scans performed on children with epilepsy can be carried out more effectively if the child is given a ‘movie’ to watch. The research, led by University College London and the epilepsy unit at Great Ormond Street Hospital, sought ways to improve the results of tests in children that combine EEG and functional magnetic [...]
